September 4 ~ 8, 2016
in Jeju, Korea
Downloads Area

Keynote Speakers

Dieter Söll

Yale University, USA

 

The Versatility of the genetic code

Peter Dedon

Massachusetts Institute of Technology (MIT), USA

 

A systems-level perspective on tRNAs, modified ribonucleosides and synonymous codons

 

Cell Biology and Modification of tRNA I

Eric Phizicky

University of Rochester, USA

 

tRNA decay pathways in yeast

Sebastian A. Leidel

Max Planck Institute for Molecular Biomedicine, Germany

 

tRNA decay pathways in yeaThe impact of wobble uridine modifications on translation and protein quality control

Eugene G. Mueller

University of Louisville, USA

 

Elucidation of the catalytic disulfide and acid base residues in 4-thiouridine synthetase

Ute Kothe

University of Lethbridge, Canada

 

The tRNA pseudouridine synthase TruB is a tRNA chaperone

Jungwook Kim

GIST, Korea

 

O-alkylation of wobble uridines in bacterial tRNA

 

Cell Biology and Modification of tRNA II

Juan Alfonzo

The Ohio State University, USA

 

Intracellular distribution of maturation factors dictates a dynamic interplay between tRNA splicing and modification in T. brucei.

Kozo Tomita

The University of Tokyo, Japan

 

Methylation of 5′-phosphate of cytoplasmic tRNAHis in human

Philippe Giegé

IBMP-CNRS, France

 

On the evolution of RNase P in eukarya

Markus T. Bohnsack

Göettingen University, Germany

 

NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation

Ru-Juan Liu

Shanghai Institutes for Biological Sciences, China

 

RNA recognition specificity of the human tRNA m5C methyltransferase NSun6

Seisuke Yamashita

The University of Tokyo, Japan

 

Mechanism of 3′-matured tRNA discrimination from 3′-immature tRNA by class-II CCA-adding enzyme

Cédric Schelcher

IBMP-CNRS, France

 

Characterization of protein-only RNase P in complex with tRNA

 

Cell Biology and Modification of tRNA III

Roland K. Hartmann

Philipps-Universität Marburg, Germany

 

Aquifex aeolicus RNase P – a cold case finally solved

Dirk Iwata-Reuyl

Portland State University, USA

 

Role of Archaeosine modification in Archaeal tRNA

Wei Xie

The Sun Yat-Sen University, China

 

Co-crystal structures provide mechanistic insight into the bifunctional tRNA methyltransferase Trm5a

Wim Versees

Vrije Universiteit Brussel, Belgium

 

Structural and functional insights into tRNA binding and nucleoside N1-methylation by the tRNA methyltransferase Trm10

Nayef Jarrous

The Hebrew University, Israel

 

Novel tRNA processing activities in initiation complexes of RNA polymerase III

 

tRNAomics and systems Biology

Akio Kanai

Keio University, Japan

 

tRNA gene diversity in Archaea and expansion of non-canonical V-arm-containing tRNAs in Eukaryotes

Todd M. Lowe

UCSC, USA

 

Epigenomic analysis of the complete human tRNA gene set reveals an unprecedented view of regulatory complexity

Lluís Ribas de Pouplana

IRB Barcelona, Spain

 

On the functional limits imposed upon the genetic code by tRNA

Eric Westhof

CNRS-Strasbourg University, France

 

An integrated, structure- and energy-based view of the genetic code

 

Non-canonical function of tRNA

Yohei Kirino

Thomas Jefferson University, USA

 

Repertoire, biogenesis, and function of tRNA halves in hormone-dependent cancers

Norbert Polacek

University of Bern, Sweden

 

The role of tRNA-derived fragments in stress response

Hong Gil Nam

DGIST, Korea

 

tRNA-derived fragments control aging in plants and animals

Pavel Ivanov

Harvard Medical School, USA

 

Diverse biology of tRNA-derived fragments

Susan Martinis

University of Illinois, USA

 

tRNA variable loop mimetic promotes leucyl-tRNA synthetase dependent RNA annealing to facilitate intron excision of critical
respiratory genes

Laurence Maréchal-Drouard

CNRS, France

 

RNS and tRFs, two major actors of plant development and stress response

Qi Chen

University of Nevada School of Medicine, USA

 

Sperm tRNA-derived small RNAs and RNA modifications in diet-induced epigenetic inheritance

 

Translational Regulation I

Ya-Ming Hou

Thomas Jefferson University, USA

 

tRNA methylation regulates gene expression

Yaser Hashem

IBMC-ARN CNRS / Université de Strasbourg, France

 

Structural investigation of the protein translation initiation process in pathogenic protozoa

Kozo Nagano

Nagano Research Institute of Molecular Biology, Japan

 

Conformational change of tRNA anticodonloop

Ying Huang

Nanjing Normal University, China

 

The Schizosaccharomyces pombe PPR protein Ppr10 associates with a novel protein Mpa1 and acts as a mitochondrial
translational activator

Alvaro Glavic

University of Chile, Chile

 

The levels of t6A modification modulate translation, TOR kinase activity and regulates growth

Damien Hermand

The University of Namur, Belgium

 

Feedback controls between TORC1/2 signaling and tRNA modifications by Elongator regulates nutrient dependent commitment to mitosi

 

Translational Regulation II

Tsutomu Suzuki

The university of Tokyo, Japan

 

Insights into molecular pathogenesis of mitochondrial diseases caused by tRNA modification deficiency

Baik L. Seong

Yonsei University, Korea

 

M1 RNA provides chaperoning function for the folding of C5 protein of RNase P complex for the maturation of tRNAs

Namit Ranjan

Max Max Planck Institute for Biophysical Chemistry, Germany

 

Loss of thiolation at the tRNA anticodon slows down protein synthesis by impeding decoding and translocation

Francesca Tuorto

German Cancer Research Center (DKFZ), Germany

 

Influence of Queuosine and 5-methylcytosine tRNA modifications on protein translation in mammals

Stéphanie Lalande

Institut de biologie moléculaire des plantes, CNRS, France

 

Translation inhibition by tRNA-derived RNA fragments in plants

Hak Kyun Kim

Stanford University, USA

 

A 3’ tRNA derived small RNA regulates ribosome biogenesis and cell viability

 

Special Talk

Achim Breiling

EMBO Reports

 

Transparent Publishing &Open Science: how to share reproducible data

 

tRNA, tRNA Synthetase and Diseases

Babak Javid

Tsinghua University School of Medicine, China

 

The mycobacterial indirect tRNA aminoacylation pathway is critical for antibiotic tolerance

Hovav Nechushtan

Hadassah Hebrew University Medical Center, Israel

 

Lysyl tRNA synthetase phosphorylation by EGFR and lung cancer

Min-Xin Guan

Zhejiang University School of Medicine, China

 

Mitochondrial tRNA mutations associated with deafness

Yi Shi

The Scripps Research Institute, USA

 

Hypoxia-induced angiogenesis is controlled by ATM/ATR-SerRS pathway

Kyunggon Kim

University of Ulsan, Korea

 

Proteomics analysis of thyroid tissues revealed the change of aminoacyl tRNA synthetases and its interacting proteins in follicular thyroid carcinoma and follicular adenocarcinoma

Marie Sissler

CNRS, France

 

The multiple localizations of the human mitochondrial aspartyl-tRNA synthetase and impact of disease associated mutations

Adrian Gabriel Torres

IRB Barcelona, Spain

 

Role of ‘wobble’ inosine in gene translation and disease

 

tRNA Synthetase Biology I

Michael Ibba

The Ohio State University, USA

 

Translation quality control signals coordination of multiple stress responses in Saccharomyces cerevisiae

Xiang-Lei Yang

The Scripps Research Institute, USA

 

Evolutionary gain of alanine mischarging to non-cognate tRNAs with a G4:U69 base pair

Hubert D. Becker

University of Strasbourg, France

 

Existence of two essential and functionally distinct nuclear methionyl-tRNA synthetases in Saccharomyces cerevisiae

Beom Sik Kang

Kyungpook National University, Korea

 

The crystal structure of human cytosolic methionyl-tRNA synthetase reveals a novel N-terminal linker between its GST and catalytic domains

Rajan Sankaranarayanan

Centre for Cellular and Molecular Biology, India

 

Mechanistic basis of chiral proofreading and its functional implications

 

tRNA Synthetase Biology II

Christopher S. Francklyn

University of Vermont, USA

 

The paradox of histidyl-tRNA synthetase (HARS): a model of tRNA recognition in which two distinct human diseases arise from mutant versions of the same enzyme

Myung Hee Kim

KRIBB, Korea

 

Immunoregulatory role of multi-tRNA synthetase complex against virus infection

Paul L. Fox

Cleveland Clinic, USA

 

Origin of the fused aminoacyl tRNA synthetase, glutamyl-prolyl tRNA synthetase

Ignacio Luque

CSIC and Universidad de Sevilla, Spain

 

Evidence for interaction of membrane-anchored ValRS with FoF1-ATP synthase in a prokaryote

Youngzee Song

The Scripps Research Institute, USA

 

Functional and structural investigations of a human AlaRS splice variant

Rajat Banerjee

University of Calcutta, India

 

Promoter DNA binding induces E. coli alanyl-tRNA synthetase (alaRS) oligomerization: Insight into its transcriptional regulation

Kook Son

University of Illinois, USA

 

A non-canonical function of Leucyl tRNA synthetase in skeletal myogenesis

 

Genetic Code Reprogramming and Synthetic Biology I

Shigeyuki Yokoyama

RIKEN, Japan

 

Expansion of the mammalian and bacterial genetic codes and their a9pplication in vivo and in vitro

Jason W. Chin

MRC, UK

 

 

Wenshe R. Liu

Texas A&M University, USA

 

The synthesis of structurally defined nucleosomes and its applications

Taek Jin Kang

Dongguk University, Korea

 

Degeneracy reprogramming for cell-free unnatural amino acid mutagenesis

Patrick O’Donoghue

The University of Western Ontario, Canada

 

Genetically encoded protein phosphorylation

 

Genetic Code Reprogramming and Synthetic Biology II

David A. Tirrell

Caltech, USA

 

Non-canonical amino acids in protein engineering and analysis

Lei Wang

UCSF, USA

 

Genetically encoding bioreactivity

Hee-Sung Park

KAIST, Korea

 

Designer proteins with selective chemical modifications

Min Yao

Hokkaido University, Japan

 

Template-dependent nucleotide addition in the reverse (3′–5′) direction by TLP

Tae Hyeon Yoo

Ajou University, Korea

 

Incorporation of noncanonical amino acids in response to the rare AGG codon

Takashi Ohtsuki

Okayama University, Japan

 

Phototriggered protein syntheses using DEACM-caged aminoacyl tRNAs

Rumit Maini

University of Tokyo, Japan

 

Ribosome-mediated site-specific incorporation of dipeptides and dipeptidomimetics into proteins

 

Innovative Technology

Hiroaki Suga

The University of Tokyo, Japan

 

A RaPID way to discover nonstandard macrocyclic peptides

Hyeyoon Park

Seoul National University, Korea

 

Watching single endogenous mRNA in neurons in vivo

Pyoung Oh Yoon

Bioneer Corporation, Korea

 

Idiopathic pulmonary fibrosis (IPF) drug development using SAMiRNA™, a second-generation RNAi Platform

Ahyun Son

Yonsei University, Korea

 

RNA interaction mediated protein folding vehicle: Virus-like particle (VLP) as recombinant vaccines against viral infection

Satoshi Ishida

The University of Tokyo, Japan

 

Ribozymes with tRNA recognition and aminoacylation properties

Hye Yeong Nam

Samyang Biopharmaceutical Company, Korea

 

Long circulating polymeric nanoparticles for efficient siRNA delivery in cancer therapy

Yuichi Miyoshi

Okayama University, Japan

 

Molecular beacons for detecting tRNAs

 

Therapeutic Applications of Translational Machinery

Daniel N. Wilson

University of Munich, Germany

 

Ribosome-targeting antibiotics and mechanisms of bacterial resistance

Jung Min Han

Yonsei University, Korea

 

From Leucyl-tRNA Synthetase to mTORC1 inhibitor: Overcoming mTOR resistance mutations in cancer

Hyunbo Shim

Ewha Womans University, Korea

 

Development of monoclonal antibodies against AIMP2-DX2 splice variant

Yoon Soo Chang

Yonsei University College of Medicine, Korea

 

Clinical implication and diagnostic usefulness of MRS and AIMP2-DX2 in NSCLC

 

Closing Remarks

Paul Schimmel

The Scripps Research Institute, USA

 

The broad reach of the tRNA world into new biology